Compassionate Overdose Response Summit link

The book of death talks about the cruelty of a paramedic giving naloxone full dose because it brings all withdrawal systems within seconds

Pharmo-capitalist lied about the effectiveness of naloxone

Distoring or misrepresenting overdose reversal and response data to justify new and changed formulations of opioid antagonists

Stimuate, airway, breathing, and other steps before applying naloxone

Focus on evidence base distribution (PWUD, low-threshold, high volume)

Naloxone Dosing Meeting Summary

Consider context

  • Post-overdose care, substance in the system, person's physiology and health, environment of overdose, access to EMT without law enforcement, resources available to respond (naloxone, rescue breathing)

Assess and Support breathing

  • rescue breathing can bring people back

Start low, intramuscular .4 mg/1ml or 2mg intranasal

  • stop additional naloxone when breathing is restored
  • Place person in recovery position

Care for person after

There is no alternative for this

  • Negative overdose reversals contribute to more deaths in the long term and could be the key stemming the tide of what has become an overdose endemic in the US

Healthright 360? Cleo Jenkins is an overdose prevention center (opc) that has emt volunteer opportunities

pop-up tents for safe use

have emt's on site

upset they wasted their last 20 dollars, is the most frequent response

New York research study showed no difference in survival rates between 4mg and 8mg and widthdrawal rates were higher with 8m

Prevention Point Pittsburgh

95 percent of OD in the area are fent

Limitations

  • Data from reversal reports when people come back for a refill

Misouri

Who administered? Friends was highest ranking

Michigan On Point

Acute vs sub-acute OD.

  • Sub-acute experience hypoxia

Oxygen should be the first step even in non-clinical settings

used IM naloxone in less than 17 percent of the cases, the rest was oxygen

deprioritize naloxone, and prioritize oxygenation, aggitation, and monitoring

UK

people discharged themselves and seeked drugs after naloxone

Ireland

overdosed caused by reduced breathing nad reduced consciousness that progress to cardiac arrest

  • main treatment is stimulation
  • All naloxone should be titrated
  • benzos and xylazine are not effected by naloxone so first aid and rescue breathing are the solution

heroin is slow and hypoxia, fentanuyl effects muscles and other systems?

plum medic

they will wait 5 hours in the ER and discharge themselves. need warm hand off

??

hotline, hold space while using

9 OD, less than 1 percent of calls

Medic from PGH

zofran for nausea

also BUP

user will use within 1 hour after OD recovery even with naloxone

xylezine can be reversed with naloxone, but... it's complicated

research on breathing is biased towards white men